研究概述：长期从事神经发育及孤独症谱系障碍的发病机制研究，重点关注小胶质细胞功能，并深入探讨Mll5基因在孤独症发生发展中的表观遗传调控机制。通过构建基因修饰动物模型并结合多组学分析，旨在揭示疾病关键分子通路，为孤独症的早期干预及靶向治疗提供理论依据。

发表论文：

1.Gao S, Lin Q, Liu X, Jia M, Zhang AY, Feng Z, Han L, Qiu N, Liu XX, Zhai H, Zhang H, Zhang J, Ding X, Zhang Y, Lu L, Shi J, Liu JJ, Wei YB. Mll5 haploinsufficiency attenuates microglial phagocytosis through dysregulated TREM2-SGK3-GSK3β signaling and recapitulates ASD-like behaviors in mice. Nat Commun, 2026 Apr 17. doi: 10.1038/s41467-026-71922-x. Epub ahead of print. PMID: 41997967.

2.Gao S, Gao M, Du H, Li L, An X, Shi Y, Wang X, Cong H, Han B, Zhou C, Zhou H. SARM regulates cell apoptosis and inflammation during Toxoplasma gondii infection through a multistep mechanism. Parasit Vectors, 2025, 18(1): 103.

3.Wang Y, Gao S, Pan Y. Letter to the editor for the article 'Pharmacologic prevention and therapy of postoperative paralytic ileus after gastrointestinal cancer surgery - systematic review and meta-analysis'. Int J Surg, 2024, 110(8): 5258-5259.

4.Jia X, Gao S, Liu X, Feng Z, Wang X, Lan K, Lu Y, Han L, Wei Y B, Liu J J. Alterations of the endocannabinoid system in autism spectrum disorder: A systematic review and meta-analysis. Eur Arch Psychiatry Clin Neurosci, 2025.

5.Lan K, Jia X, Gao S, Feng Z, Jia M, Yue W, Wei Y B, Liu J J. Research trends and hotspots on family caregivers of individuals with autism spectrum disorder from 2002 to 2022: A bibliometric analysis. J Child Adolesc Psychiatr Nurs, 2025, 38(1): e70008.