研究概述：

主要从事脑部疾病创新药物/递药系统研究。研究方向包括：以核酸i-motif/G-四链体结构为AD治疗靶点的小分子药物开发、新型脑靶向纳米递药系统的构建以及多糖/中药小分子的抗AD活性机制研究。

发表论文：

1.Ji D, Zhang J, Liang J, Huang ZS, Shu B, Li D. Efficient strategy for alleviating neuronal apoptosis and oxidative stress damage of Alzheimer’s disease through dual targeting BCL-2 gene promoter i-motif and β-amyloid. Redox Biol. 2025, 82, 103600.

2.Ji D, Zhang J, Liang J, Wang J, Li X, Huang ZS, Li D. New therapeutic method for alleviating damage of acute kidney injury through BCL-2 gene promoter i-motif. Int. J. Mol. Sci. 2024, 34, 116042.

3.Feng Y^#, Li X^#, Ji D^#, Tian J, Peng Q, Shen Y, Xiao Y. Functionalised penetrating peptide-chondroitin sulphate‑gold nanoparticles: Synthesis, characterization, and applications as an anti-Alzheimer's disease drug. Int. J. Biol. Macromol. 2023; 230, 123125.

4.Ji D^#, Wu X^#, Li D^#, Liu P, Zhang S, Gao D, Gao F, Zhang M, Xiao Y. Protective effects of chondroitin sulphate nano-selenium on a mouse model of Alzheimer's disease. Int. J. Biol. Macromol. 2020; 154, 233-245.