研究概述：主要从事儿童实体肿瘤及相关神经系统并发症的转化医学研究，重点聚焦儿童颅内生殖细胞肿瘤的发生发展、耐药转移及肿瘤相关神经损伤机制。围绕肿瘤免疫微环境、代谢重编程及神经–免疫互作，综合运用蛋白质组学、单细胞转录组学、空间转录组学、脂质组学及第三代测序等多组学技术，系统解析儿童难治复发肿瘤的分子调控网络与关键生物学通路。

招生专业/方向：肿瘤学，生物医学，分子生物学，生物信息学，基础医学

发表论文：

1.Manfei Liang; Clara Hody; Vanessa Yammine; Romuald Soin; Yuqiu Sun; Xing Lin; Xiaoying Tian; Romane Meurs; Camille Perdrau; Nadège Delacourt; Marina Oumalis; Fabienne Andris; Louise Conrard; Véronique Kruys; Cyril Gueydan; eIF4EHP promotes Ldh mRNA translation in and fruit fly adaptation to hypoxia, EMBO reports, 2023, 24(e56460): 1-15 

2.Manfei Liang; Qingyou Zhao; Yixiang Song; Jianchao Chen; Exploring mRNA translation strategies for hypoxia adaptation across distantly related metazoans, Epigenomics, 2023,

3.Ying Wang; Lei Wang; Manfei Liang; Zhongkai Xu; Yiheng Xue; Guoqin Liu; Verification of blood flow path reconstruction mechanism in distal sigmoid colon and rectal cancer after high IMA ligation through preoperative and postoperative comparison by manual subtraction CTA, European Journal of Surgical Oncology, 2023, 49(7): 1268-1274

专利：多重荧光PCR检测肿瘤微卫星不稳定状态试剂盒

软件著作权：基因变异驱动的微卫星不稳定性（MSI）评分软件[简称：MSIScore]1.0

科研项目：山东省自然青年项目，山东省重点竞争性创新平台