研究概述：

主要从事功能纳米材料与生物医用高分子的设计、构建及其在疾病诊疗中的应用研究。研究方向涵盖纳米医学、仿生纳米酶与功能性水凝胶的开发，重点探索利用肿瘤、创面及脑损伤等病理微环境特征，构建具有可控反应性与多功能整合的治疗平台。目前，以第一作者身份发表9篇SCI论文，其中8篇中科院一区，总影响因子92.1。

发表论文：

1.Xingchen Li^#, Xia Zhang^#, Lei Song, Yuan Li, Annan Liu, Lei Li, Maja D. Nesic ̌,́ Dan Li, Liping Peng, Chunyan Wang*, and Quan Lin*. Nanozymes as tumor energy homeostasis disruptor to augment cascade catalytic therapy. ACS Nano, 2024, 18, 34656-34670.

2.Xingchen Li, Zifan Meng, Lin Guan, Annan Liu, Lei Li, Maja D. Neˇsi´c, Bai Yang, Wenrui Qu*, Quan Lin*. Glucose-Responsive hydrogel optimizing Fenton reaction to eradicate multidrug-resistant bacteria for infected diabetic wound healing. Chemical Engineering Journal, 2024, 487, 150545.

3.Xingchen Li^#, Ming Hao^#, Annan Liu, Lei Li, Maja D. Neˇsi´c, Bai Yang, Weiwei Liu*, Quan Lin*. Dual-activity nanozyme as an oxygen pump to alleviate tumor hypoxia and enhance photodynamic/ NIR-II photothermal therapy for sniping oral squamous cell carcinoma. Acta Biomaterialia, 2024, 1742-7061.

4.Xingchen Li, Yuxuan Zhang, Annan Liu, Lei Li, Xiaoyu Yang, Yuan Wang, Yuechen Zhao, Andrei V. Zvyagin, Tiejun Wang, Quan Lin. Nanozyme as tumor energy homeostasis disruptor mediated ferroptosis for high-efficiency radiotherapy. Journal of Colloid And Interface Science, 688 (2025) 44–58. (Cover Article)

5.Xingchen Li^#, Yangliu Lin^#, Zhe Yang, Lin Guan, Ze Wang, Annan Liu, Bai Yang, Lu Tang*, Quan Lin*. Cancer cell membrane biomimetic nanosystem for homologous targeted dual-mode imaging and combined therapy. Journal of Colloid And Interface Science, 2023, 652, 770–779.

6.Xingchen Li^#, Lin Guan^#, Xiaoli Li, Xiaolan Ou, Wenlai Guo, Andrei V. Zvyagin, Wenrui Qu*, Bai Yang, Quan Lin*. A hierarchical hydrogel dressing with continuous biochemical gradient for immunoregulation, nerve repair and angiogenesis of refractory diabetes wounds. Chinese Chemical Letters, 2024, 110661.

7.Xingchen Li^#, Yuxuan Pang^#, Lin Guan, Lei Li, Yanlin Zhu, Andrew K. Whittaker, Bai Yang, Song Zhu*, Quan Lin*. Mussel-inspired antimicrobial hydrogel with cellulose nanocrystals/tannic acid modified silver nanoparticles for enhanced calvarial bone regeneration. International Journal of Biological Macromolecules, 2024, 132419.

8.Xingchen Li, Zhe Yang, Linan Fang, Chengyuan Ma, Yue Zhao, Hou Liu, Songtian Che, Andrei V. Zvyagin, Bai Yang, and Quan Lin. Hydrogels Composite with Different Dimensional Nanoparticles for Bone Regeneration. Macromolecular Rapid Communications, 2021, 2100362.

9.Ming Hao^#, Xingchen Li^#, Xinxin Zhang, Boqiang Tao, He Shi, Jianing Wu, Yuyang Li, Xiang Li, Shuangji Li, Han Wu, Jingcheng Xiang, Dongxu Wang, Weiwei Liu, Guoqing Wang. Tongue squamous cell carcinoma-targeting Au-HN-1 nanosystem for CT imaging and photothermal therapy. International Journal of Oral Science, (2025) 17:9.