研究概述:利用小鼠模型,主要从事小鼠听力发育及功能相关研究
发表论文:
1.Liu Z*, Zhang H*, Hong G*, Bi X, Hu J, Zhang T, An Y, Guo N, Dong F, Xiao Y, Li W, Zhao X, Chu B, Guo S, Zhang X, Chai R, Fu X. Inhibition of Gpx4-mediated ferroptosis alleviates cisplatin-induced hearing loss in C57BL/6 mice. Mol Ther. 2024 May 1;32(5):1387-1406.
2.Liu Z*, Mo F*, Dong X, Chen G, Gao J, Zhang J. Progressive degeneration of the retina in Loxl3 mutant mouse model of Stickler syndrome. Dev Biol. 2023 Mar;495:54-62.
3.Li P*, Liu Z*, Wang J, Bi X, Xiao Y, Qiao R, Zhou X, Guo S, Wan P, Chang M, Hong G, Liu Z, Ming X, Gao J, Fu X. Gstm1/Gstt1 is essential for reducing cisplatin ototoxicity in CBA/CaJ mice. FASEB J. 2022 Jun;36(6):e22373.
4.Liu Z, Bai X, Wan P, Mo F, Chen G, Zhang J, Gao J. Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss. Front Cell Dev Biol. 2021 Jun 4;9:683495.
主持课题:
1.国家自然科学基金,青年基金项目,ACSL4介导的毛细胞脂肪酸代谢在听觉功能维持中的作用机制研究,2024-01至2026-12,30万;
2.山东省自然科学基金,面上项目,脂肪酸代谢在毛细胞发育及功能维持中的作用机制研究,2025-01至2027-12,10万;