研究概述：离子调控在组织发育分化与再生修复中的作用。肌骨系统/脑骨系统互作。中药药理学研究。

发表论文：

1.Z.Chen, J. Xu, P. Hu, W. Du, W. Zhou, J. Xu, B. Dai, Y. Ruan, L. Qin. Defective Cystic Fibrosis Transmembrane Conductance Regulator Accelerates Skeletal Muscle Aging by Impairing Autophagy/Myogenesis. J Cachexia, Sarcopenia Muscle, 2025, Feb.

2.Z.Chen, X. Liu, X. Feng, A. lyu, W. Zhou. A systematic pharmacological strategy-based to decode the synergistic mechanism of 7,4′-dihydroxyffavone in combination with vitamin D3 against asthma. J Ethnopharmacol, 2025 Feb.

3. J. Guo, H. Yao, L. Chang, W. Zhu, Y. Zhang, X. Li, B. Yang, B. Dai, L. Lei, Z. Chen, Ye Li, L. Zheng, W. Liu, Y. Su, L. Qin, J. Xu. Magnesium Nanocomposite Hydrogel Reverses the Pathologies to Enhance Mandible Regeneration. Adv Mater, 2025 Jan;37(2).

4.Z. Jin, Z. Chen, T. Liang, W. Liu, Z. Shan, D. Tan, J. Chen, J. Hu, L. Qin^* J. Xu^*, Accelerated Fracture Healing Accompanied with Traumatic Brain Injury: A Review of Clinical Studies, Animal Models and Potential Mechanisms. Journal of Orthopaedic Translation, 2025 Jan.

5.L. Zhou, J. Xu, W. Tong, J. XU, Z. Chen, C. Wen, L. Qin; Engineered biochemical cues of regenerative biomaterials to enhance endogenous stem/progenitor cells (ESPCs)-mediated articular cartilage repair. Bioact Mater. 2023.

6.B. Dai, J. Xu, X. Li, L. Huang, J. Wang, W. Tong, Y. Li, X. He, Z. Chen, Q. Jiang, L. Qin. Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis. Nat Commun. 2022 Jan.

7.J. Zhang, Z. Chen, L. Zhang, X. Zhao, Z. Liu, W. Zhou. A systems-based analysis to explore the multiple mechanisms of Shan Zha for treating human diseases. Food Funct. 2021 Feb 15;12(3):1176-1191. (co-first).

8.Z. Chen, X. LI, J. JIN, W. Zhou, J. Chen, KL FOK; Connective tissue growth factor mediates spermatogonial migration associated with differentiation. BBA Molecular Cell Research, 2020 Jul;1867(7):118708.

9.W. Zhou, Z. Chen, G. Zhang, Z. Liu. Systems pharmacology-based approach for dissecting the mechanisms of pyrazine components in Maotai liquor. Bioscience Reports, 2019, 39 (10). (co-first).

主持课题：

山东省自然科学基金, 青年项目, ZR2024QH621, 口服苏糖酸镁调节生物钟改善认知障碍, 2024-12 至 2027-12,在研, 主持;