研究概述:药物结构设计、药物的合成以及药物作用机理研究。
发表论文:
1.Liyun Zhao, Qi Liang, Ye He, et al. HDAC/JAK dual target inhibitors of cancer-related targets: the success of nonclearable linked pharmacophore mode, Bioorganic Chemistry. (2022) 106181.
2.Liyun Zhao, Xuan Xiong, Li Liu, et al. Recent research and development of DYRK1A inhibitors, Chinese Chemical Letters. 33 (4) (2022) 1841-1849.
3.Qing Nian, Jinhao Zeng, Li He, Yu Chen, Zhiqiang Zhang, Rodrigues-Lima Fernando, Liyun Zhao*, Xuanlin Feng* ,Jianyou Shi*. A small molecule inhibitor targeting SHP2 mutations for the lung carcinoma. Chinese Chemical Letters. 32 (2021) 1645-1652.
4.Liyun Zhao, Zhen Ke, Dengfeng Zou, et al. Synthesis and Anticancer Mechanism of a Cu(II) Compound Based on 5-Aminotetrazole-1-acetic Acid Against Hepatocellular Carcinoma Cells, Journal of Inorganic and Organometallic Polymers and Materials. 28 (6) (2018) 2819-2824.
5.Yu Xiang, Swapna Naik, Liyun Zhao, et al. Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases, Medicinal Research Reviews. 44 (4) (2024) 1404-1445.
6.Zhenzhen Zhang, Xin Liu, Liyun Zhao, et al. A review on the treatment of multiple myeloma with small molecular agents in the past five years, European Journal of Medicinal Chemistry. 229 (2022) 114053.