研究概述:开发智能药物递送系统,实现肿瘤部位靶向给药和可控释放、肿瘤免疫治疗联合研究。
发表论文:
1.Yan J, Wang G*, Xie L*, Tian H, Li J, Li B, Sang W, Li W, Zhang Z, Dai Y. Engineering Radiosensitizer-Based Metal-Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy. Adv Mater. 2022 Mar;34(10):e2105783.
2.Yan J*, Li W*, Tian H*, Li B*, Yu X, Wang G, Sang W, Dai Y. Metal-Phenolic Nanomedicines Regulate T-Cell Antitumor Function for Sono-Metabolic Cancer Therapy. ACS Nano. 2023 Aug 8;17(15):14667-14677.
3.Jie Yan*, Bei Li*, Piaoping Yang*, Jun Lin*, Yunlu Dai*. Progress in Light-Responsive Lanthanide Nanoparticles toward Deep Tumor Theranostics. Advanced Functional Materials. 2021;31(42):2104325. Wang G*, Yan J*, Tian H*, Li B*, Yu X, Feng Y, Li W, Zhou S, Dai Y. Dual-Epigenetically Relieving the MYC-Correlated Immunosuppression via an Advanced Nano-Radiosensitizer Potentiates Cancer Immuno-Radiotherapy. Adv Mater. 2024 May;36(19):e2312588.
4.Li W*, Yan J*, Tian H, Li B, Wang G, Sang W, Zhang Z, Zhang X, Dai Y. A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance. Bioact Mater. 2022 Sep 24;22:34-46.