青年骨干

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耿红岩

副教授

骨干人才

邮箱:hygeng@sdfmu.edu.cn

 


研究概述:通过运用光遗传、钙成像、电生理、行为学、病理模型等技术研究神经精神疾病如阿尔茨海默病、帕金森病、抑郁症等疾病的神经环路机制,以及运动、空间学习记忆的产生,情绪记忆的形成与存储等脑环路基础。

发表论文

1.Wang, W.Q., Zhao, H.X., Shen, X.L., Zheng, L.Z., Geng, H.Y.* (2024) Estrogen Receptor Alpha–Expressing Neurons in Bed Nucleus of the Stria Terminalis and Hypothalamus Encoding Aggression and Mating. eNeuro. 11,11.

2.Abdurahman, M., Xiao,Y.H., Zeng, L.Z., and Geng, H.Y.* (2024).Neurotensin modulates emotional valence assignment in basolateral amygdala through neuromodulator gain. Neurosci Bull.

3.Tan, P.Y., Shen X.-L., Zeng, L.Z., Weng, X.C., and Geng, H.Y.* (2024) Pharmacotherapy for the Core Symptoms of Autism Spectrum Disorders. J Zhejiang Univ-Sc B. 25(11):956-971.

4.Kou, Z.Q., Chen, C.Y., Abdurahman, M., Weng, X.C., Hu, C., and Geng, H.Y.* (2023). The Claustrum Controls Motor Activity Through Anterior Cingulate Cortex Input and Local Circuit Synchronization in a Preparatory Manner. Neurosci Bull 39, 1591-1594.

5.Chen, C.Y., Yang, G.Y., Tu, H.X., Weng, X.C., Hu, C., and Geng, H.Y.* (2023). The cognitive dysfunction of claustrum on Alzheimer's disease: A mini-review. Front Aging Neurosci 15, 1109256.

6.Yang, G.Y. #, Geng, H.Y. #, and Hu, C. (2022). Targeting 5-HT as a Potential Treatment for Social Deficits in Autism. Neurosci Bull 38, 1263-1266.

7.Geng, H.Y., Arbuthnott, G., Yung, W.H., and Ke, Y. (2021). Long-Range Monosynaptic Inputs Targeting Apical and Basal Dendrites of Primary Motor Cortex Deep Output Neurons. Cereb Cortex. 10.1093/cercor/bhab460.

8.Mu, M.D. #, Geng, H.Y. #, Rong, K.L. #, Peng, R.C., Wang, S.T., Geng, L.T., Qian, Z.M., Yung, W.H., and Ke, Y. (2020). A limbic circuitry involved in emotional stress-induced grooming. Nat Commun 11, 2261.

9.Cui, Q. #, Li, Q. #, Geng, H.Y. #, Chen, L., Ip, N.Y., Ke, Y., and Yung, W.H. (2018). Dopamine receptors mediate strategy abandoning via modulation of a specific prelimbic cortex-nucleus accumbens pathway in mice. Proc Natl Acad Sci U S A 115, E4890-E4899.

10.Geng, H.Y. #, Zhang, J. #, Yang, J.M., Li, Y., Wang, N., Ye, M., Chen, X.J., Lian, H., and Li, X.M. (2017). Erbb4 Deletion from Medium Spiny Neurons of the Nucleus Accumbens Core Induces Schizophrenia-Like Behaviors via Elevated GABAA Receptor alpha1 Subunit Expression. J Neurosci 37, 7450-7464.



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