研究概述：采用多种技术手段，从事神经系统尤其是脑血管病发病机制与防治研究。

发表论文：

1. Sun BL^*, Wang LH, Yang T, Sun JY, Mao LL, Yang MF, Yuan H, Colvin RA, Yang XY. Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases. Prog Neurobiol. 2018 Apr-May;163-164:118-143. 

2. An C, Shi Y, Li P, Hu X, Gan Y, Stetler RA, Leak RK, Gao Y, Sun BL^#, Zheng P^#, Chen J^#. Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair. Prog Neurobiol. 2014 Apr;115:6-24. 

3. Sun J, Song Y, Wang M, Zhao P, Gao F, Li J, Yang M, Yuan H, Sun B^#, Wang Y^#. Quantitative and Noninvasive Detection of SAH-Related MiRNA in Cerebrospinal Fluids In Vivo Using SERS Sensors Based on Acupuncture-Based Technology. ACS Appl Mater Interfaces. 2022 Aug 17;14(32):37088-37100. 

4. Wang J, Cai Y, Sun J, Feng H, Zhu X, Chen Q, Gao F, Ni Q, Mao L^#, Yang M^#, Sun B^#. Administration of intramuscular AAV-BDNF and intranasal AAV-TrkB promotes neurological recovery via enhancing corticospinal synaptic connections in stroke rats. Exp Neurol. 2023 Jan;359:114236. 

5. Wang C, Wang C, Wang M, Wang M, Ni Q, Sun J, Sun B^#, Wang Y^#. Minimally Invasive Real-Time Monitoring for Rapid and Sensitive Diagnosis of Spinal Cord Injury. ACS Sens. 2024 Oct 25;9(10):5058-5068.

6. Wang J, Zhu M, Sun J, Feng L, Yang M, Sun B^#, Mao L^#. Gene therapy of adeno-associated virus (AAV) vectors in preclinical models of ischemic stroke. CNS Neurosci Ther. 2023 Dec;29(12):3725-3740.

7. Mao L, Wang K, Zhang P, Ren S, Sun J, Yang M, Zhang F, Sun B ^# .Carbonyl Reductase 1 Attenuates Ischemic Brain Injury by Reducing Oxidative Stress and Neuroinflammation. Transl Stroke Res. 2021 Oct;12(5):711-724. 

8. Han Q, Wang C, Liu J, Wang C, Zhang H, Ni Q, Sun J, Wang Y, Sun B^#. Application of Nanozymes and its Progress in the Treatment of Ischemic Stroke. Transl Stroke Res. 2024 Oct;15(5):880-892. 

9. Liu J, Sun J, Song Y, Wang M, Zhao P, Wang W, Yang M, Wang Y, Song Y, Sun B^#. Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery. ACS Chem Neurosci. 2023 Apr 10.

10. Zhao P, Sun J, Zhao S, Song Y, Gao F, Wang H, Ni Q, Wang Y^#, Sun B^#. SERS-based immunoassay based on gold nanostars modified with 5,5'-dithiobis-2-nitrobenzoic acid for determination of glial fibrillary acidic protein. Mikrochim Acta. 2021 Nov 23;188(12):428. 

主持课题：

国家自然科学基金,面上项目，脑靶向工程化BMSCs外泌体miRNA let-7a-5p调控FASLG缓解SAH后神经血管单元损伤及机制研究，2025-01至2028-12；