研究概述：主要研究方向为阿尔茨海默病的早期诊断生物标志物及发病机制研究。

发表论文：

1.Zhao M Q, Li Y J, Han X D, Li C, Wang P, Wang J, Hou T, Wang Y, Cong L, Wardlaw J, Launer L, Song L^*, Du Y^*, Qiu C. Association of enlarged perivascular spaces with cognitive function in dementia‐free older adults: A population‐based study. Alzheimers Dement (Amst). 2024,16(3):e12618.

2.Chen Z, Xie Q, Wang J, Wang Y, Zhang H, Li C, Wang Y, Cong L, Tang S, Hou T, Song L^*, Du Y^*, Qiu C. Mapping grey matter and cortical thickness alterations associated with subjective cognitive decline and mild cognitive impairment among rural-dwelling older adults in China: A population-based study. Neuroimage Clin. 2024:44:103691. doi: 10.1016/j.nicl.2024.103691.

3.Li C, Wang J, Han X, Li Y, Liu K, Zhao M, Gong T, Hou T, Wang Y, Cong L, Song L^*, Du Y^*. Development and validation of a diagnostic model for cerebral small vessel disease among rural older adults in China. Front Neurol. 2024 Jul 5;15:1388653.

4.Wang J, Han X, Li Y, Fa W, Zhao M, Li C, Mao M, Hou T, Wang Y, Cong L, Song L^*, Du Y^*. Qiu C. Strategic Lacunes Associated With Mild Cognitive Impairment in Rural Chinese Older Adults: A Population-Based Study. Stroke. 2024, 55(5): 1288-1298.

5.Li C, Zhang H, Wang J, Han X, Liu C, Li Y, Gong T, Hou T, Wang Y, Cong L, Kalpouzos G, Wardlaw J, Song L^*, Du Y^*, Qiu C. Choroid Plexus Volume in Rural Chinese Older Adults: Distribution and Association With Cardiovascular Risk Factors and Cerebral Small Vessel Disease. J Am Heart Assoc. 2024 Oct 18:e035941.

6.Song L, Han X, Li Y, Han X, Zhao M, Li C, Wang P, Wang J, Dong Y, Cong L, Han X, Hou T, Liu K, Wang Y, Qiu C^*, Du Y^*. Thalamic gray matter volume mediates the association between KIBRA polymorphism and olfactory function among older adults: a population-based study. Cereb Cortex. 2023, 33(7): 3664-3673.

7.Han X, Li Y, Wang P, Han X, Zhao M, Wang J, Li C, Tian N, Han X, Hou T, Wang Y, Song L^*, Du Y^*, Qiu C. Insulin Resistance-Varying Associations of Adiposity Indices with Cerebral Perfusion in Older Adults: A Population-Based Study. J Nutr Health Aging. 2023, 27(3): 219-227.

8.Song L^#, Tang S^#, Han X, Jiang Z, Dong L, Liu C, Liang X, Dong J, Qiu C, Wang Y^*, Du Y^*. KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a. Nat Commun. 2019, 10(1): 0-1639.

9.Song L^#, Tang S^#, Dong L, Han X, Cong L, Dong J, Han X, Zhang Q, Wang Y^*, Du Y^*. The Neuroprotection of KIBRA in Promoting Neuron Survival and Against Amyloid beta-Induced Apoptosis. Front Cell Neurosci. 2019, 13: 0-137.

10.Wang P^#, Song L^#, Wang K, Han X, Cong L, Wang Y, Zhang L, Yan Z, Tang S^*, Du Y^*. Prevalence and associated factors of poor sleep quality among Chinese older adults living in a rural area: a population-based study. Aging Clin Exp Res. 2019, 32(1): 125-131.