研究概述：长期从事精神医学和睡眠医学领域的公共卫生政策、发病机制、流行病学特征和干预策略研究。提出了干预病理性记忆的新模式，开发了快速抗抑郁的新靶点，建立了在睡眠中治疗精神心理疾病的新策略，改变了传统的治疗理念。主持了多项科研项目，包括国家任务和国际合作项目，涉及病理性情感记忆的唤起和消退的神经生物学机制、睡眠-觉醒障碍的发病机制及干预措施等。获得了教育部高等学校科学研究优秀成果奖（自然科学奖）一等奖、国家自然科学奖二等奖等重大奖项。

发表论文：

1. Liu X, Xiong W, Ye M, Lu T, Yuan K, Chang S, Han Y, Wang Y^#, Lu L^#, Bao Y^#. Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets. Signal Transduct Target Ther. 2023 Dec 6;8(1):441.

2. Bao Y, Sun Y, Meng S, Shi J, Lu L. 2019-nCoV epidemic: address mental health care to empower society. Lancet. 2020 Feb 22;395(10224):e37-e38.

3. Zhao Y, Shi L, Jiang Z, Zeng N, Mei H, Lu Y, Yang J, Jin F, Ni S, Wu S, Su S, Zheng Y, Yuan K, Yan W, Sun S, Meng S, Sun J, Khan Z, Aarsland D, Shi J, Li X^#, Bao Y^#, Lu L^#. The phenotype and prediction of long-term physical, mental and cognitive COVID-19 sequelae 20 months after recovery, a community-based cohort study in China. Mol Psychiatry. 2023 Apr;28(4):1793-1801.

4. Bao Y, Meng S, Shi J, Lu L. Control of fentanyl-related substances in China. Lancet Psychiatry. 2019 Jul;6(7):e15.

5. Liu L, Ni SY, Yan W, Lu QD, Zhao YM, Xu YY, Mei H, Shi L, Yuan K, Han Y, Deng JH, Sun YK, Meng SQ, Jiang ZD, Zeng N, Que JY, Zheng YB, Yang BN, Gong YM, Ravindran AV, Kosten T, Wing YK, Tang XD, Yuan JL, Wu P, Shi J, Bao YP, Lu L. Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: A systematic review, meta-analysis and call for action. EClinicalMedicine. 2021 Oct;40:101111.

6. Yue JL, Yuan K, Bao YP, Meng SQ, Shi L, Fang Q, Guo XJ, Cao L, Sun YK, Lu TS, Zeng N, Yan W, Han Y, Sun J, Shi J, Kosten TR^#, Xue YX^#, Wu P^#, Lu L^#. The effect of a methadone-initiated memory reconsolidation updating procedure in opioid use disorder: A translational study. EBioMedicine. 2022 Nov;85:104283.

7. Wang Z, Chen WH, Li SX, He ZM, Zhu WL, Ji YB, Wang Z, Zhu XM, Yuan K, Bao YP, Shi L, Meng SQ, Xue YX, Xie W, Shi J, Yan W^#, Wei H^#, Lu L^#, Han Y^#. Gut microbiota modulates the inflammatory response and cognitive impairment induced by sleep deprivation. Mol Psychiatry. 2021 Nov;26(11):6277-6292

8. Xue YX^*, Luo YX^*, Wu P^*, Shi HS, Xue LF, Chen C, Zhu WL, Ding ZB, Bao YP, Shi J, Epstein DH, Shaham Y, Lu L. A memory retrieval-extinction procedure to prevent drug craving and relapse. Science. 2012 Apr 13;336(6078):241-5.