研究领域：
1.生物节律异常与神经系统疾病的相关研究；
2.早产儿缺氧脑白质损伤修复机制；
3.DEAF1突变导致神经发育异常的相关机制；
个人介绍：
李培军，教授，博士生导师。2011年于美国乔治城大学获得生理学和生物物理学专业博士学位。先后在美国华盛顿国家儿童医疗机构的神经科学研究中心和华盛顿退伍军人事务部医学中心从事科研工作。2018年1月回国，目前在山东第一医科大学脑科学与类脑研究院从事生物节律与神经系统疾病特别是癫痫等方面的研究工作。主持两项国家自然科学基金面上项目。学术成果发表在Neuron，PNAS，Nature Neuroscience，Nature Communications等期刊。
代表性论文：
1. Lu Deng#, Hong Jiang#, Jingjing Lin, Di Xu, Ailin Qi, Qing Guo, Pingping Li, Xinshi Wang, Judy S. Liu*, Xiaoqin Fu*, Peijun Li*, Conditional knockout of CLOCK in inhibitory neurons may affect predisposition to epilepsy in mice, Neurobiology of Disease，2024 Feb 28;193:106457. doi: 10.1016/j.nbd.2024.106457.
2. Ping He, Dongyan Zhou, Shuangya Chen, Shuting Zhong, Zhiyan Xia, Di Xu, Xiaokun Li, Peijun Li*, Cong Wang*, FGF is required for Purkinje cell development and function in the crebellum, iScience 2024 Jan 26;27(2):109039. doi: 10.1016/j.isci.2024.109039.
3. Li Li, Ying Su, Siyuan Wang, Chengyu Wang, Naqi Ruan, Zhiyan Hu, Xin Cheng, Jiajia Chen, Kaiming Yuan, Peijun Li*, Pei Fan*, Neonatal di-(2-ethylhexyl) phthalate exposure induces permanent alterations in secretory CRH neuron characteristics in the hypothalamus paraventricular region of adult male rats. Experimental Neurology, 2024 Feb;372:114616. doi: 10.1016/j.expneurol.2023.114616.
4. Muran Wang#, Peijun Li#, Zewen Li#，Beatriz S. da Silva, Wu Zheng, Zhenghua Xiang, Yan He, Tao Xu, Cristina Cordeiro, Lu Deng, Yuwei Da, Mengqian Ye, Zhiqing Lin, Jianhong Zhou, Xuzhao Zhou, Fenfen Ye, Rodrigo A. Cunha, Jiangfan Chen*, Wei Guo*, Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula, Nature Communications，2023 Apr 5;14(1):1880
5. Huiping Shang# , Peijun Li# , Xiangxiang Lin , Qionghui Cai, Zhihui Li, Lu Deng , Yue Song, Jiang-fan Chen*, Jianhong Zhou* , Neuronal and astrocytic CB1R signaling differentially modulates goal-directed behavior and working memory by distinct temporal mechanisms, Neuropsycopharmacology, 2023, January 24, doi: 10.1038/ s41386-023-01533-3.
6. Xueying Li, Wanhua Qiu, Lu Deng, Jingjing Lin，Wenting Huang， Yuchen Xu, Mulan Zhang, Nigel C Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li*, Xinshi Wang*，11β-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice. Journal of Translational Medicine, 2022, Sep 5; 20(1): 406-18.
7. Peijun Li*#, Xiaoqin Fu#, Milagros J. Tenga, Julian Curiel, Brandon Martin, Tammy N. Tsuchida, Amanda Yaun, Suresh N. Magge, Chima Oluigbo, Amy Kao, Tesfaye G. Zelleke, Dewi T. Depositario-Cabacar, Howard P. Goodkin, Svetlana Ghimbovich, Susan Knoblach, Chen-Ying Ho, William D. Gaillard, Molly M. Huntsman, Gregorio Valdez and Judy S. Liu*. Loss of Clock results in dysfunction of brain circuits that underlie focal epilepsy. Neuron. 2017 Oct 11;96(2):387-401
8. Marzieh Zonouzi, Joseph Scafidi, Peijun Li, Brian McEllin, Jorge Edwards, Jeffrey L Dupree, Lloyd Harvey, Dandan Sun, Christian A Hübner, Stuart Cull-Candy, Mark Farrant, Vittorio Gallo. Local GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nature Neuroscience, 2015 May; 18(5):674-82
9. Jean-Marie Mangin, Peijun Li, Joseph Scafidi, and Vittorio Gallo. Experience-dependent regulation of NG2 progenitors in the developing barrel cortex. Nature Neuroscience. 2012 Sep; 15(9): 1192–1194
10. Peijun Li, Uwe Rudolph, and Molly M. Huntsman. Long-term sensory deprivation selectively rearranges functional inhibitory circuits in mouse barrel cortex. Proc Natl Acad Sci USA. 2009 Jul 21;106(29):12156-61
主持科研项目：
1. 国家自然科学基金面上项目，神经元与少突胶质前体细胞在早产儿缺氧性脑损伤修复中的参与机理，2021/01-2024/12，55 万元，主持。
2.国家自然科学基金面上项目，生物钟蛋白 CLOCK 缺失引发癫痫的机制及其治疗初探，2019/01-2022/12，56 万元，主持。
联系方式：pjli@sdfmu.edu.cn 0531-59567870
