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李培军

发布日期:2024-04-02    作者:     来源:     点击:

个人简介:

教授,博士生导师。2011年于美国乔治城大学获得生理学和生物物理学专业博士学位。先后在美国华盛顿国家儿童医疗机构的神经科学研究中心和华盛顿退伍军人事务部医学中心从事科研工作。2018年1月回国,目前在山东第一医科大学脑科学与类脑研究院从事生物节律与神经系统疾病特别是癫痫等方面的研究工作。主持两项国家自然科学基金面上项目。学术成果发表在Neuron,PNAS,Nature Neuroscience,Nature Communications等期刊。

主要研究领域:

1. 生物节律异常与神经系统疾病的相关研究;

2. 早产儿缺氧脑白质损伤修复机制

3. DEAFI突变导致神经发育异常的相关机制。

代表性论文:

1. Lu Deng#, Hong Jiang#, Jingjing Lin, Di Xu, Ailin Qi, Qing Guo, Pingping Li, Xinshi Wang, Judy S. Liu*, Xiaoqin Fu*, Peijun Li*, Conditional knockout of CLOCK in inhibitory neurons may affect predisposition to epilepsy in mice, Neurobiology of Disease,2024 Feb 28;193:106457. doi: 10.1016/j.nbd.2024.106457 (SCI 2区,影响因子6.1,最后通讯);

2. Ping He, Dongyan Zhou, Shuangya Chen, Shuting Zhong, Zhiyan Xia, Di Xu, Xiaokun Li, Peijun Li*, Cong Wang*, FGF is required for Purkinje cell development and function in the crebellum, iScience 2024 Jan 26;27(2):109039. doi: 10.1016/j.isci.2024.109039. (SCI 2区,影响因子5.75,共同通讯);

3. Li Li, Ying Su, Siyuan Wang, Chengyu Wang, Naqi Ruan, Zhiyan Hu, Xin Cheng, Jiajia Chen, Kaiming Yuan, Peijun Li*, Pei Fan*, Neonatal di-(2-ethylhexyl) phthalate exposure induces permanent alterations in secretory CRH neuron characteristics in the hypothalamus paraventricular region of adult male rats. Experimental Neurology, 2024 Feb;372:114616. doi: 10.1016/j.expneurol.2023.114616. (SCI 2区,影响因子 5.3, 共同通讯);

4. Muran Wang#, Peijun Li#, Zewen Li#,Beatriz S. da Silva, Wu Zheng, Zhenghua Xiang, Yan He, Tao Xu, Cristina Cordeiro, Lu Deng, Yuwei Da, Mengqian Ye, Zhiqing Lin, Jianhong Zhou, Xuzhao Zhou, Fenfen Ye, Rodrigo A. Cunha, Jiangfan Chen*, Wei Guo*, Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula, Nature Communications,2023 Apr 5;14(1):1880 (SCI 1区,影响因子17.69,共同一作);

5. Huiping Shang# , Peijun Li# , Xiangxiang Lin , Qionghui Cai, Zhihui Li, Lu Deng , Yue Song, Jiang-fan Chen*, Jianhong Zhou* , Neuronal and astrocytic CB1R signaling differentially modulates goal-directed behavior and working memory by distinct temporal mechanisms, Neuropsycopharmacology, 2023, January 24, doi: 10.1038/ s41386-023-01533-3.SCI 1区,影响因子 8.29共同一作);

6. Xueying Li, Wanhua Qiu, Lu Deng, Jingjing Lin,Wenting Huang, Yuchen Xu, Mulan Zhang, Nigel C Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li*, Xinshi Wang*,11β-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice. Journal of Translational Medicine, 2022, Sep 5; 20(1): 406-18. (SCI 2区,影响因子 8.44,共同通讯);

7. Peijun Li*#, Xiaoqin Fu#, Milagros J. Tenga, Julian Curiel, Brandon Martin, Tammy N. Tsuchida, Amanda Yaun, Suresh N. Magge, Chima Oluigbo, Amy Kao, Tesfaye G.Zelleke, Dewi T. Depositario-Cabacar, Howard P. Goodkin, Svetlana Ghimbovich, Susan Knoblach, Chen-Ying Ho, William D. Gaillard, Molly M. Huntsman, Gregorio Valdez and Judy S. Liu*. Loss of Clock results in dysfunction of brain circuits that underlie focal epilepsy. Neuron. 2017 Oct 11;96(2):387-401 (SCI 1区,影响因子 18.688,第一作者,共同通讯);

  8. Marzieh Zonouzi, Joseph Scafidi, Peijun Li, Brian McEllin, Jorge Edwards, Jeffrey L Dupree, Lloyd Harvey, Dandan Sun, Christian A Hübner, Stuart Cull-Candy, Mark Farrant, Vittorio Gallo. Local GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nature Neuroscience, 2015 May; 18(5):674-82 SCI 1区,影响因子 21.2);

  9. Jean-Marie Mangin, Peijun Li, Joseph Scafidi, and Vittorio Gallo. Experience-dependent regulation of NG2 progenitors in the developing barrel cortex. Nature Neuroscience. 2012 Sep; 15(9): 1192–1194  (SCI 1区,影响因子 21.2);

  10. Peijun Li, Uwe Rudolph, and Molly M. Huntsman. Long-term sensory deprivation selectively rearranges functional inhibitory circuits in mouse barrel cortex. Proc Natl Acad Sci USA. 2009 Jul 21;106(29):12156-61 (SCI 1区,影响因子12.779,第一作者)。

招生招聘

实验室招聘神经生物学(分子生物学、电生理、光遗传、动物行为学等)相关背景的博士后和副研究员。同时欢迎对本实验室研究方向感兴趣的本科生前来实习和报考研究生。

联系方式:

  pjli@sdfmu.edu.cn